We're solving one of the greatest challenges facing biology research
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The use of Foetal Bovine Serum (FBS) is ubiquitous in cell culture research. FBS is harvested from cow fetuses, with one fetal cow yielding up to one standard 500mL bottle of FBS. With worldwide demand for FBS a staggering 800,000 litres per annum and climbing, that's a lot of dead cows.
FBS isn't just ethically contentious, it's also expensive, with prices having increased by over 300% in recent years. It's not ideal for scientific research either. Being an animal-derived product, FBS varies between batches, is subject to contamination and influences the behaviour of the cells it is used to culture. This affects the consistency and reliability of important research, as well as scientists' ability to translate their results into the clinical space. |
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"Arguably media with a well defined composition and free of any serum or natural extract are the best choice for culturing cells, specifically for research purposes, but these media are expensive and their use is not widespread"
(Gstraunthaler, Lindl and van der Valk, 2013)
Introducing FRS - Foetal Bovine Serum Replacement Solution
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Media City Scientific is developing FRS™️, a universal and chemically defined substitute to Foetal Bovine Serum. FRS™️ can grow a broad range of cells, outperforming other commercially available cell culture serum substitutes. FRS™️ provides cleanliness, consistency and reproducibility without sacrificing the efficacy of Foetal Bovine Serum. These characteristics are not only a pre-requisite for good research, but also crucial for translation of results to emerging therapeutic areas such as cell therapies. The Food and Drug Administration (FDA) and European Medicines Agency (EMA) encourage the reduction or replacement of Foetal Bovine Serum in the manufacture of human biological medicinal products due to poor reproducibility and the possible presence of contaminants such as nonhuman pathogens. Explore how you can partner with Media City Scientific to phase out Foetal Bovine Serum in your laboratory and organisation. |
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Universal Performance Across Multiple Cell Types
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Chemically Defined - Unparalleled Reproducibility
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Contaminant Free
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Low Cost
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