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How much fetal cow goes into 1 x bottle of FBS?
It depends on the age of the fetal cow in question, but 150mL-500mL; that’s how much FBS you can harvest from 1 x fetal cow. Really puts into perspective all those bottles of FBS that arrive neatly frozen by the pallet into some companies. There are lots of reasons I’d like to see cell culture’s reliance on FBS disappear; improved reproducibility for experiments and smooth regulatory approval for cell therapies are often called out by my collaborators who want to go chemically defined. But there’s also an emotional ick factor once you start being unable to stop yourself from calculating the number of fetal cows that went into your FBS order. If you’re a Sydney-based scientist, this cow thinks you should know: the third and final stage of external testing for FBS Replacement Solution by Media City Scientific is kicking off September 1st. I provide the animal-free and chemically defined product, you provide the cells. You’ll get one to one support in going chemically defined - even if your process doesn’t ultimately involve FRS - and we’ll be able to launch a product that has been heavily street-tested, so we can be super transparent with scientists about how it works across a broad range of cells. No use case too basic or too unusual, we’ve seen everything from cell culture courses & CHO cells to organoid-based therapies destined for scaled, cGMP manufacturing. Just send me a message ☺️
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What's been happening?Sharing the Media City journey has been important to us because we want to encourage the next generation of scientists to establish companies that will advance scientific research. Check back regularly for the "building in public" updates on what it looks like to establish a scientific company. Archives
January 2026
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